重组小鼠 IL-6 蛋白
产品名称： 重组小鼠 IL-6 蛋白
英文名称： Recombinant Mouse IL-6 Protein
产品编号： C230582
产品价格： 1855
产品产地： 美国
品牌商标： Arcegen
更新时间： 2025-03-06T11:29:33
使用范围： null
| 规格 | 价格 |
| 2μg | 445.0 |
| 10ug | 1855.0 |
| 50ug | 5565.0 |
| 100ug | 7865.0 |
| 500ug | 19665.0 |
- 联系人 : 钟珍
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- 邮编 : 201314
- 所在区域 : 上海
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Product description
Interleukin-6 (IL-6) protein is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. It stimulates B-cell differentiation and antibody production, acts synergistically with IL-3 in megakaryocyte development and platelet production, and regulates bone metabolism. IL-6 signals through an IL-6 receptor system consisting of two chains, IL-6Rα and gp130.
Specifications
|
Catalog Number |
C230582E |
C230582S |
C230582M |
C230582L |
C230582T |
|
Specifications |
2 μg |
10 μg |
50 μg |
100 μg |
500 μg |
Properties
|
Synonyms |
Interleukin-6, IL-6, B-cell differentiation factor, B-cell stimulatory factor 2, BSF2; CTL differentiation factor, HSF, IFNB2, IFN-beta-2. |
|
Source |
E.coli-derived mouse IL-6 protein, Phe25-Thr211, with an N-terminal Met. |
|
Accession |
P08505 |
|
Molecular Weight |
Approximately 21.7 kDa. |
|
AA Sequence |
MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT |
|
Endotoxin |
< 1.0 EU/μg by the LAL method. |
|
Purity |
> 97% as determined by SDS-PAGE and HPLC. |
|
Biological Activity |
The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is less than 0.02 ng/mL, corresponding to a specific activity of > 5 × 107 IU/mg. Fully biologically active when compared to standard. |
|
Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in 30 mM Acetic Acid, pH 3.0, 150 mM NaCl, 5% Trehalose, 0.02% Tween-20. |
|
Tag |
No tag. |
|
Physical Appearance |
Lyophilized powder. |
|
Reconstitution |
Centrifuge tubes before opening. Use sterile deionized water to redissolve, reformulate to the concentration of 0.1-1.0 mg/mL, can be further diluted according to subsequent experiments. For long-term storage, it is recommended to add carrier protein (0.1% BSA) to the dilution buffer. |
Storage
The product should be stored at -25~-15℃ for 1 year from date of receipt.
After redissolution, the product would be stored at -85~-65℃ for 3 months or at 2~8℃ for 7 days.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Notes
1. Please operate with lab coats and disposable gloves, for your safety.
2. This product is for research use only.